Combining docking with pharmacophore filtering for improved virtual screening

BACKGROUND: Virtual screening is used to distinguish potential leads from inactive compounds in a database of chemical samples. One method for accomplishing this is by docking compounds into the structure of a receptor binding site in order to rank-order compounds by the quality of the interactions...

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Detalles Bibliográficos
Autores principales: Peach, Megan L, Nicklaus, Marc C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152774/
https://www.ncbi.nlm.nih.gov/pubmed/20298524
http://dx.doi.org/10.1186/1758-2946-1-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152774/
https://www.ncbi.nlm.nih.gov/pubmed/20298524
http://dx.doi.org/10.1186/1758-2946-1-6

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