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Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model

BACKGROUND: The peptide neurotransmitter N-acetylaspartylglutamate (NAAG) is widely expressed throughout the vertebrate nervous system, including the pain processing neuraxis. Inhibitors of NAAG peptidases are analgesic in animal models of pain. However, the brain regions involved in NAAG's ana...

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Detalles Bibliográficos
Autores principales: Adedoyin, Mary O, Vicini, Stefano, Neale, Joseph H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152775/
https://www.ncbi.nlm.nih.gov/pubmed/20860833
http://dx.doi.org/10.1186/1744-8069-6-60