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Threshold selection in gene co-expression networks using spectral graph theory techniques

BACKGROUND: Gene co-expression networks are often constructed by computing some measure of similarity between expression levels of gene transcripts and subsequently applying a high-pass filter to remove all but the most likely biologically-significant relationships. The selection of this expression...

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Detalles Bibliográficos
Autores principales: Perkins, Andy D, Langston, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152776/
https://www.ncbi.nlm.nih.gov/pubmed/19811688
http://dx.doi.org/10.1186/1471-2105-10-S11-S4