Proviral HIV-genome-wide and pol-gene specific Zinc Finger Nucleases: Usability for targeted HIV gene therapy

BACKGROUND: Infection with HIV, which culminates in the establishment of a latent proviral reservoir, presents formidable challenges for ultimate cure. Building on the hypothesis that ex-vivo or even in-vivo abolition or disruption of HIV-gene/genome-action by target mutagenesis or excision can irre...

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Detalles Bibliográficos
Autor principal: Wayengera, Misaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152896/
https://www.ncbi.nlm.nih.gov/pubmed/21781315
http://dx.doi.org/10.1186/1742-4682-8-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152896/
https://www.ncbi.nlm.nih.gov/pubmed/21781315
http://dx.doi.org/10.1186/1742-4682-8-26

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