Reduced spinal microglial activation and neuropathic pain after nerve injury in mice lacking all three nitric oxide synthases

BACKGROUND: Several studies have investigated the involvement of nitric oxide (NO) in acute and chronic pain using mice lacking a single NO synthase (NOS) gene among the three isoforms: neuronal (nNOS), inducible (iNOS) and endothelial (eNOS). However, the precise role of NOS/NO in pain states remai...

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Detalles Bibliográficos
Autores principales: Kuboyama, Kazuya, Tsuda, Makoto, Tsutsui, Masato, Toyohara, Yumiko, Tozaki-Saitoh, Hidetoshi, Shimokawa, Hiroaki, Yanagihara, Nobuyuki, Inoue, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152900/
https://www.ncbi.nlm.nih.gov/pubmed/21756313
http://dx.doi.org/10.1186/1744-8069-7-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152900/
https://www.ncbi.nlm.nih.gov/pubmed/21756313
http://dx.doi.org/10.1186/1744-8069-7-50

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