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Reduced spinal microglial activation and neuropathic pain after nerve injury in mice lacking all three nitric oxide synthases
BACKGROUND: Several studies have investigated the involvement of nitric oxide (NO) in acute and chronic pain using mice lacking a single NO synthase (NOS) gene among the three isoforms: neuronal (nNOS), inducible (iNOS) and endothelial (eNOS). However, the precise role of NOS/NO in pain states remai...
Autores principales: | Kuboyama, Kazuya, Tsuda, Makoto, Tsutsui, Masato, Toyohara, Yumiko, Tozaki-Saitoh, Hidetoshi, Shimokawa, Hiroaki, Yanagihara, Nobuyuki, Inoue, Kazuhide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152900/ https://www.ncbi.nlm.nih.gov/pubmed/21756313 http://dx.doi.org/10.1186/1744-8069-7-50 |
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