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A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle
BACKGROUND: Mitochondria are a vital component of eukaryotic cells and their dysfunction is implicated in a large number of metabolic, degenerative and age-related human diseases. The mechanism or these disorders can be difficult to elucidate due to the inherent complexity of mitochondrial metabolis...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152903/ https://www.ncbi.nlm.nih.gov/pubmed/21714867 http://dx.doi.org/10.1186/1752-0509-5-102 |