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A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle

BACKGROUND: Mitochondria are a vital component of eukaryotic cells and their dysfunction is implicated in a large number of metabolic, degenerative and age-related human diseases. The mechanism or these disorders can be difficult to elucidate due to the inherent complexity of mitochondrial metabolis...

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Detalles Bibliográficos
Autores principales:	Smith, Anthony C, Robinson, Alan J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152903/ https://www.ncbi.nlm.nih.gov/pubmed/21714867 http://dx.doi.org/10.1186/1752-0509-5-102

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