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Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes

BACKGROUND: Hepatic inflammation and degeneration induced by lipid depositions may be the major cause of nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the effects of saturated and unsaturated fatty acids (FA) on apoptosis in primary rat hepatocytes. METHODS: The primary ra...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Yang, Xia, Shi, Hongyang, Dong, Lei, Bai, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152932/
https://www.ncbi.nlm.nih.gov/pubmed/21787405
http://dx.doi.org/10.1186/1476-511X-10-122