Cargando…

Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring

BACKGROUND: The preimplantation embryo is sensitive to culture conditions in vitro and poor maternal diet in vivo. Such environmental perturbations can have long-lasting detrimental consequences for offspring health and physiology. However, early embryo susceptibility to other aspects of maternal he...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Charlotte L, Teeling, Jessica L, Perry, V Hugh, Fleming, Tom P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152940/
https://www.ncbi.nlm.nih.gov/pubmed/21771319
http://dx.doi.org/10.1186/1741-7007-9-49