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Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring
BACKGROUND: The preimplantation embryo is sensitive to culture conditions in vitro and poor maternal diet in vivo. Such environmental perturbations can have long-lasting detrimental consequences for offspring health and physiology. However, early embryo susceptibility to other aspects of maternal he...
Autores principales: | Williams, Charlotte L, Teeling, Jessica L, Perry, V Hugh, Fleming, Tom P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152940/ https://www.ncbi.nlm.nih.gov/pubmed/21771319 http://dx.doi.org/10.1186/1741-7007-9-49 |
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