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Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients

BACKGROUND: Members of the urokinase-type plasminogen activator (uPA) system are up-regulated in various solid malignant tumors. High antigen levels of uPA, its inhibitor PAI-1 and its receptor uPAR have recently been shown to be associated with poor prognosis in soft-tissue sarcoma (STS) patients....

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Detalles Bibliográficos
Autores principales: Kotzsch, Matthias, Magdolen, Viktor, Greither, Thomas, Kappler, Matthias, Bache, Matthias, Lautenschläger, Christine, Füssel, Susanne, Eckert, Alexander W, Luther, Thomas, Baretton, Gustavo, Würl, Peter, Taubert, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152967/
https://www.ncbi.nlm.nih.gov/pubmed/21702998
http://dx.doi.org/10.1186/1471-2407-11-273