Cargando…

Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients

BACKGROUND: Members of the urokinase-type plasminogen activator (uPA) system are up-regulated in various solid malignant tumors. High antigen levels of uPA, its inhibitor PAI-1 and its receptor uPAR have recently been shown to be associated with poor prognosis in soft-tissue sarcoma (STS) patients....

Descripción completa

Detalles Bibliográficos
Autores principales:	Kotzsch, Matthias, Magdolen, Viktor, Greither, Thomas, Kappler, Matthias, Bache, Matthias, Lautenschläger, Christine, Füssel, Susanne, Eckert, Alexander W, Luther, Thomas, Baretton, Gustavo, Würl, Peter, Taubert, Helge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152967/ https://www.ncbi.nlm.nih.gov/pubmed/21702998 http://dx.doi.org/10.1186/1471-2407-11-273

Ejemplares similares

Co-detection of members of the urokinase plasminogen activator system in tumour tissue and serum correlates with a poor prognosis for soft-tissue sarcoma patients
por: Taubert, H, et al.
Publicado: (2010)

Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients
por: Hahnel, Antje, et al.
Publicado: (2012)

Elevated tumor and serum levels of the hypoxia-associated protein osteopontin are associated with prognosis for soft tissue sarcoma patients
por: Bache, Matthias, et al.
Publicado: (2010)

Association of Tissue mRNA and Serum Antigen Levels of Members of the Urokinase-Type Plasminogen Activator System with Clinical and Prognostic Parameters in Prostate Cancer
por: Al-Janabi, Omar, et al.
Publicado: (2014)

Prognostic impact of urokinase-type plasminogen activator system components in clear cell renal cell carcinoma patients without distant metastasis
por: Fuessel, Susanne, et al.
Publicado: (2014)

A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients
por: Rot, Swetlana, et al.
Publicado: (2011)

Expression of human Piwi-like genes is associated with prognosis for soft tissue sarcoma patients
por: Greither, Thomas, et al.
Publicado: (2012)

Low HIF-1α and low EGFR mRNA Expression Significantly Associate with Poor Survival in Soft Tissue Sarcoma Patients; the Proteins React Differently
por: Rot, Swetlana, et al.
Publicado: (2018)

The autoactivation of human single-chain urokinase-type plasminogen activator (uPA)
por: Torres-Paris, Constanza, et al.
Publicado: (2023)

CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients
por: Greither, Thomas, et al.
Publicado: (2017)

Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation
por: Cunningham, Orla, et al.
Publicado: (2009)

Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer
por: Asuthkar, Swapna, et al.
Publicado: (2013)

Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer
por: Micalet, Auxtine, et al.
Publicado: (2023)

GP88/PGRN Serum Levels Are Associated with Prognosis for Oral Squamous Cell Carcinoma Patients
por: Greither, Thomas, et al.
Publicado: (2021)

A Key Role for the Urokinase Plasminogen Activator (uPA) in Invasive Group A Streptococcal Infection
por: Sanderson-Smith, Martina L., et al.
Publicado: (2013)

The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer
por: Banys-Paluchowski, Malgorzata, et al.
Publicado: (2019)

Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics through Binding to the Different Forms of uPA
por: Dreymann, Nico, et al.
Publicado: (2022)

Effects of osteopontin inhibition on radiosensitivity of MDA-MB-231 breast cancer cells
por: Hahnel, Antje, et al.
Publicado: (2010)

Inhibition of urokinase plasminogen activator “uPA” activity alters ethanol consumption and conditioned place preference in mice
por: Al Maamari, Elyazia, et al.
Publicado: (2014)

Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) promote neurorepair in the ischemic brain
por: Merino, Paola, et al.
Publicado: (2017)

Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas.
por: Bouchet, C., et al.
Publicado: (1994)

MiR-155-5p and MiR-203a-3p Are Prognostic Factors in Soft Tissue Sarcoma
por: Greither, Thomas, et al.
Publicado: (2020)

Urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1) in breast cancer - correlation with traditional prognostic factors
por: Lampelj, Maja, et al.
Publicado: (2015)

uPA-mediated plasminogen activation is enhanced by polyphosphate
por: Whyte, Claire S., et al.
Publicado: (2020)

Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
por: Mahmood, Niaz, et al.
Publicado: (2018)

A Pilot Study of Urokinase-Type Plasminogen Activator (uPA) Overexpression in the Brush Cytology of Patients with Malignant Pancreatic or Biliary Strictures
por: Gibbs, John F., et al.
Publicado: (2009)

Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK)
por: Santos, Nancy Dos, et al.
Publicado: (2007)

Expression of survivin detected by immunohistochemistry in the cytoplasm and in the nucleus is associated with prognosis of leiomyosarcoma and synovial sarcoma patients
por: Taubert, Helge, et al.
Publicado: (2010)

Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells
por: Grismayer, Bettina, et al.
Publicado: (2012)

Elevated HERV-K Expression in Soft Tissue Sarcoma Is Associated with Worsened Relapse-Free Survival
por: Giebler, Maria, et al.
Publicado: (2018)

Correlation of Serum Levels of Urokinase Activation Plasminogen (uPA) and Its Inhibitor (PAI-1) with Hormonal and HER-2 Status in the Early Invasive Breast Cancer
por: Pusina, Sadat
Publicado: (2018)

Investigation of the Prognostic Role of Carbonic Anhydrase 9 (CAIX) of the Cellular mRNA/Protein Level or Soluble CAIX Protein in Patients with Oral Squamous Cell Carcinoma
por: Eckert, Alexander W., et al.
Publicado: (2019)

Prognostic impact of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) in cytosols and pellet extracts derived from 892 breast cancer patients
por: de Witte, J H, et al.
Publicado: (1999)

Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells
por: Soelch, Susanne, et al.
Publicado: (2021)

TEM8 functions as a receptor for uPA and mediates uPA-stimulated EGFR phosphorylation
por: Zhang, Lian-Cheng, et al.
Publicado: (2018)

P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients
por: Kappler, Matthias, et al.
Publicado: (2017)

Prognostic impact of mRNA levels of LGR5 transcript variants in OSCC patients
por: Rot, Swetlana, et al.
Publicado: (2019)

Explication of the roles of prostate health index (PHI) and urokinase plasminogen activator (uPA) as diagnostic and predictor tools for prostate cancer in equivocal PSA range of 4–10 ng/mL
por: Nassir, Anmar M., et al.
Publicado: (2020)

Prognostic significance of urokinase (uPA) and its inhibitor PAI-1 for survival in advanced ovarian carcinoma stage FIGO IIIc
por: Kuhn, W, et al.
Publicado: (1999)

Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs)
por: Wang, Li, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_t039l3tk2rp9b39goe30shfd52