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Low Molecular Weight Opioid Peptide Esters Could be Developed as a New Class of Analgesics
Low molecular weight opioid peptide esters (OPE) could become a class of analgesics with different side effect profiles than current opiates. OPE may have sufficient plasma stability to cross the blood brain barrier (BBB), undergo ester hydrolysis and produce analgesia. OPE of dipeptides, tyr-pro an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153123/ https://www.ncbi.nlm.nih.gov/pubmed/21863129 http://dx.doi.org/10.4137/PMC.S6803 |