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Low Molecular Weight Opioid Peptide Esters Could be Developed as a New Class of Analgesics

Low molecular weight opioid peptide esters (OPE) could become a class of analgesics with different side effect profiles than current opiates. OPE may have sufficient plasma stability to cross the blood brain barrier (BBB), undergo ester hydrolysis and produce analgesia. OPE of dipeptides, tyr-pro an...

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Detalles Bibliográficos
Autor principal:	Goldberg, Joel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Libertas Academica 2011
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153123/ https://www.ncbi.nlm.nih.gov/pubmed/21863129 http://dx.doi.org/10.4137/PMC.S6803

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