Smurf1 Inhibits Mesenchymal Stem Cell Proliferation and Differentiation into Osteoblasts through JunB Degradation

Ubiquitin ligase Smurf1-deficient mice develop an increased-bone-mass phenotype in an age-dependent manner. It was reported that such a bone-mass increase is related to enhanced activities of differentiated osteoblasts. Although osteoblasts are of mesenchymal stem cell (MSC) origin and MSC prolifera...

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Detalles Bibliográficos
Autores principales: Zhao, Lan, Huang, Jian, Guo, Ruolin, Wang, Yi, Chen, Di, Xing, Lianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153132/
https://www.ncbi.nlm.nih.gov/pubmed/20200942
http://dx.doi.org/10.1002/jbmr.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153132/
https://www.ncbi.nlm.nih.gov/pubmed/20200942
http://dx.doi.org/10.1002/jbmr.28

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