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Novel Cytotoxic Vectors Based on Adeno-Associated Virus

Vectors based on adeno-associated virus (AAV) are promising tools for gene therapy. The production of strongly toxic vectors, for example for cancer-directed gene transfer, is often unfeasible due to uncontrolled expression of toxic genes in vector-producing cells. Using an approach based on transcr...

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Detalles Bibliográficos
Autores principales: Kohlschütter, Johannes, Michelfelder, Stefan, Trepel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153187/
https://www.ncbi.nlm.nih.gov/pubmed/22069574
http://dx.doi.org/10.3390/toxins2122754