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Strategy for Treating Motor Neuron Diseases Using a Fusion Protein of Botulinum Toxin Binding Domain and Streptavidin for Viral Vector Access: Work in Progress

Although advances in understanding of the pathogenesis of amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) have suggested attractive treatment strategies, delivery of agents to motor neurons embedded within the spinal cord is problematic. We have designed a strategy based on the...

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Detalles Bibliográficos
Autores principales: Drachman, Daniel B., Adams, Robert N., Balasubramanian, Uma, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153189/
https://www.ncbi.nlm.nih.gov/pubmed/22069580
http://dx.doi.org/10.3390/toxins2122872