The Zinc-Dependent Protease Activity of the Botulinum Neurotoxins

The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are the causative agents of botulism. Following exposure, the neurotoxin binds and enters peripheral cholinergic nerve endings and specifically and selectively cleaves one or more SNARE proteins to produce...

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Detalles Bibliográficos
Autores principales: Lebeda, Frank J., Cer, Regina Z., Mudunuri, Uma, Stephens, Robert, Singh, Bal Ram, Adler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153231/
https://www.ncbi.nlm.nih.gov/pubmed/22069621
http://dx.doi.org/10.3390/toxins2050978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153231/
https://www.ncbi.nlm.nih.gov/pubmed/22069621
http://dx.doi.org/10.3390/toxins2050978

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