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The Zinc-Dependent Protease Activity of the Botulinum Neurotoxins
The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are the causative agents of botulism. Following exposure, the neurotoxin binds and enters peripheral cholinergic nerve endings and specifically and selectively cleaves one or more SNARE proteins to produce...
Autores principales: | Lebeda, Frank J., Cer, Regina Z., Mudunuri, Uma, Stephens, Robert, Singh, Bal Ram, Adler, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153231/ https://www.ncbi.nlm.nih.gov/pubmed/22069621 http://dx.doi.org/10.3390/toxins2050978 |
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