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Autoproteolytic Activation of Bacterial Toxins

Protease domains within toxins typically act as the primary effector domain within target cells. By contrast, the primary function of the cysteine protease domain (CPD) in Multifunctional Autoprocessing RTX-like (MARTX) and Clostridium sp. glucosylating toxin families is to proteolytically cleave th...

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Detalles Bibliográficos
Autor principal: Shen, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153235/
https://www.ncbi.nlm.nih.gov/pubmed/22069620
http://dx.doi.org/10.3390/toxins2050963