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Characterization of SNARE Cleavage Products Generated by Formulated Botulinum Neurotoxin Type-A Drug Products

The study evaluated substrate cleavage product(s) generated by three botulinum neurotoxin serotype A (BoNT/A) medicinal drug products utilizing a novel and highly specific, light-chain activity, high-performance liquid chromatography (LCA-HPLC) method. Samples were reacted with a commercially availa...

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Detalles Bibliográficos
Autores principales: Hunt, Terrence, Rupp, David, Shimizu, Gary, Tam, Karen, Weidler, Julia, Xie, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153282/
https://www.ncbi.nlm.nih.gov/pubmed/22069680
http://dx.doi.org/10.3390/toxins2082198