Staphylococcal Superantigen (TSST-1) Mutant Analysis Reveals that T Cell Activation Is Required for Biological Effects in the Rabbit Including the Cytokine Storm

Staphylococcal superantigens (sAgs), such as toxic shock syndrome toxin 1 (TSST-1), induce massive cytokine production, which may result in toxic shock syndrome (TSS) and sepsis. Recently, we reported that in vitro studies in human peripheral blood mononuclear cells (PBMC) do not reflect the immunol...

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Detalles Bibliográficos
Autores principales: Stich, Norbert, Waclavicek, Martina, Model, Nina, Eibl, Martha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153295/
https://www.ncbi.nlm.nih.gov/pubmed/22069685
http://dx.doi.org/10.3390/toxins2092272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153295/
https://www.ncbi.nlm.nih.gov/pubmed/22069685
http://dx.doi.org/10.3390/toxins2092272

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