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Genetic and Hormonal Control of Bone Volume, Architecture, and Remodeling in XXY Mice

Klinefelter syndrome is the most common chromosomal aneuploidy in men (XXY karyotype, 1 in 600 live births) and results in testicular (infertility and androgen deficiency) and nontesticular (cognitive impairment and osteoporosis) deficits. The extent to which skeletal changes are due to testosterone...

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Detalles Bibliográficos
Autores principales: Liu, Peter Y, Kalak, Robert, Lue, YanHe, Jia, Yue, Erkkila, Krista, Zhou, Hong, Seibel, Markus J, Wang, Christina, Swerdloff, Ronald S, Dunstan, Colin R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153317/
https://www.ncbi.nlm.nih.gov/pubmed/20499350
http://dx.doi.org/10.1002/jbmr.104