Estrogens Attenuate Oxidative Stress and the Differentiation and Apoptosis of Osteoblasts by DNA-Binding-Independent Actions of the ERα

Estrogens diminish oxidative stress in bone and bone marrow, attenuate the generation of osteoblasts, and decrease the prevalence of mature osteoblast apoptosis. We have searched for the molecular mechanism of these effects using as tools a mouse model bearing an estrogen receptor α (ERα) knock-in m...

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Detalles Bibliográficos
Autores principales: Almeida, Maria, Martin-Millan, Marta, Ambrogini, Elena, Bradsher, Robert, Han, Li, Chen, Xiao-Dong, Roberson, Paula K, Weinstein, Robert S, O'Brien, Charles A, Jilka, Robert L, Manolagas, Stavros C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153331/
https://www.ncbi.nlm.nih.gov/pubmed/19821774
http://dx.doi.org/10.1359/jbmr.091017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153331/
https://www.ncbi.nlm.nih.gov/pubmed/19821774
http://dx.doi.org/10.1359/jbmr.091017

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