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Progressive Ankylosis Protein (ANK) in Osteoblasts and Osteoclasts Controls Bone Formation and Bone Remodeling

The progressive ankylosis gene (ank) encodes a transmembrane protein that transports intracellular inorganic pyrophosphate (PP(i)) to the extracellular milieu. ank/ank mice, which express a truncated nonfunctional ANK, showed a markedly reduced bone mass, bone-formation rate, and number of tartrate-...

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Detalles Bibliográficos
Autores principales: Kim, Hyon Jong, Minashima, Takeshi, McCarthy, Edward F, Winkles, Jeffrey A, Kirsch, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153348/
https://www.ncbi.nlm.nih.gov/pubmed/20200976
http://dx.doi.org/10.1002/jbmr.60