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Progressive Ankylosis Protein (ANK) in Osteoblasts and Osteoclasts Controls Bone Formation and Bone Remodeling
The progressive ankylosis gene (ank) encodes a transmembrane protein that transports intracellular inorganic pyrophosphate (PP(i)) to the extracellular milieu. ank/ank mice, which express a truncated nonfunctional ANK, showed a markedly reduced bone mass, bone-formation rate, and number of tartrate-...
Autores principales: | Kim, Hyon Jong, Minashima, Takeshi, McCarthy, Edward F, Winkles, Jeffrey A, Kirsch, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153348/ https://www.ncbi.nlm.nih.gov/pubmed/20200976 http://dx.doi.org/10.1002/jbmr.60 |
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