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Mouse BMD Quantitative Trait Loci Show Improved Concordance With Human Genome-wide Association Loci When Recalculated on a New, Common Mouse Genetic Map

Bone mineral density (BMD) is a heritable trait, and in mice, over 100 quantitative trait loci (QTLs) have been reported, but candidate genes have been identified for only a small percentage. Persistent errors in the mouse genetic map have negatively affected QTL localization, spurring the developme...

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Detalles Bibliográficos
Autores principales: Ackert-Bicknell, Cheryl L, Karasik, David, Li, Qian, Smith, Randy V, Hsu, Yi-Hsiang, Churchill, Gary A, Paigen, Beverly J, Tsaih, Shirng-Wern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153351/
https://www.ncbi.nlm.nih.gov/pubmed/20200990
http://dx.doi.org/10.1002/jbmr.72