Impaired Osteoblast Function in GPRC6A Null Mice

GPRC6A is a widely expressed orphan G protein–coupled receptor that senses extracellular amino acids, osteocalcin, and divalent cations in vitro. GPRC6A null (GPRC6A(−/−)) mice exhibit multiple metabolic abnormalities including osteopenia. To investigate whether the osseous abnormalities are a direc...

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Detalles Bibliográficos
Autores principales: Pi, Min, Zhang, Lishu, Lei, Shu-Feng, Huang, Min-Zhao, Zhu, Wenyu, Zhang, Jianghong, Shen, Hui, Deng, Hong-Wen, Quarles, L Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153369/
https://www.ncbi.nlm.nih.gov/pubmed/19874200
http://dx.doi.org/10.1359/jbmr.091037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153369/
https://www.ncbi.nlm.nih.gov/pubmed/19874200
http://dx.doi.org/10.1359/jbmr.091037

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