Fluorescent Risedronate Analogues Reveal Bisphosphonate Uptake by Bone Marrow Monocytes and Localization Around Osteocytes In Vivo

Bisphosphonates are effective antiresorptive agents owing to their bone-targeting property and ability to inhibit osteoclasts. It remains unclear, however, whether any non-osteoclast cells are directly affected by these drugs in vivo. Two fluorescent risedronate analogues, carboxyfluorescein-labeled...

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Detalles Bibliográficos
Autores principales: Roelofs, Anke J, Coxon, Fraser P, Ebetino, Frank H, Lundy, Mark W, Henneman, Zachary J, Nancollas, George H, Sun, Shuting, Blazewska, Katarzyna M, Bala, Joy Lynn F, Kashemirov, Boris A, Khalid, Aysha B, McKenna, Charles E, Rogers, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153397/
https://www.ncbi.nlm.nih.gov/pubmed/20422624
http://dx.doi.org/10.1359/jbmr.091009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153397/
https://www.ncbi.nlm.nih.gov/pubmed/20422624
http://dx.doi.org/10.1359/jbmr.091009

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