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A Double Blind, Placebo-Controlled, Randomized Crossover Study of the Acute Metabolic Effects of Olanzapine in Healthy Volunteers

BACKGROUND AND RATIONALE: Atypical antipsychotics exhibit metabolic side effects including diabetes mellitus and obesity. The adverse events are preceded by acute worsening of oral glucose tolerance (oGTT) along with reduced plasma free fatty acids (FFA) and leptin in animal models. It is unclear wh...

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Detalles Bibliográficos
Autores principales: Albaugh, Vance L., Singareddy, Ravi, Mauger, David, Lynch, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153475/
https://www.ncbi.nlm.nih.gov/pubmed/21857944
http://dx.doi.org/10.1371/journal.pone.0022662