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Chronic Myeloid Leukemia Patients in Prolonged Remission following Interferon-α Monotherapy Have Distinct Cytokine and Oligoclonal Lymphocyte Profile

Before the era of tyrosine kinase inhibitors (TKIs), interferon-alpha (IFN-α) was the treatment of choice in chronic myeloid leukemia (CML). Curiously, some IFN-α treated patients were able to discontinue therapy without disease progression. The aim of this project was to study the immunomodulatory...

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Detalles Bibliográficos
Autores principales: Kreutzman, Anna, Rohon, Peter, Faber, Edgar, Indrak, Karel, Juvonen, Vesa, Kairisto, Veli, Voglová, Jaroslava, Sinisalo, Marjatta, Flochová, Emília, Vakkila, Jukka, Arstila, Petteri, Porkka, Kimmo, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153480/
https://www.ncbi.nlm.nih.gov/pubmed/21857985
http://dx.doi.org/10.1371/journal.pone.0023022