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A Robust Statistical Method for Association-Based eQTL Analysis

BACKGROUND: It has been well established that theoretical kernel for recently surging genome-wide association study (GWAS) is statistical inference of linkage disequilibrium (LD) between a tested genetic marker and a putative locus affecting a disease trait. However, LD analysis is vulnerable to sev...

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Detalles Bibliográficos
Autores principales: Jiang, Ning, Wang, Minghui, Jia, Tianye, Wang, Lin, Leach, Lindsey, Hackett, Christine, Marshall, David, Luo, Zewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153488/
https://www.ncbi.nlm.nih.gov/pubmed/21858027
http://dx.doi.org/10.1371/journal.pone.0023192