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The Initiation of GTP Hydrolysis by the G-Domain of FeoB: Insights from a Transition-State Complex Structure

The polytopic membrane protein FeoB is a ferrous iron transporter in prokaryotes. The protein contains a potassium-activated GTPase domain that is essential in regulating the import of iron and conferring virulence to many disease-causing bacteria. However, the mechanism by which the G-domain of Feo...

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Detalles Bibliográficos
Autores principales: Ash, Miriam-Rose, Maher, Megan J., Guss, J. Mitchell, Jormakka, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153494/
https://www.ncbi.nlm.nih.gov/pubmed/21858085
http://dx.doi.org/10.1371/journal.pone.0023355