Including Total EGFR Staining in Scoring Improves EGFR Mutations Detection by Mutation-Specific Antibodies and EGFR TKIs Response Prediction

Epidermal growth factor receptor (EGFR) is a novel target for therapy in subsets of non-small cell lung cancer, especially adenocarcinoma. Tumors with EGFR mutations showed good response to EGFR tyrosine kinase inhibitors (TKIs). We aimed to identify the discriminating capacity of immunohistochemica...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Shang-Gin, Chang, Yih-Leong, Lin, Jou-Wei, Wu, Chen-Tu, Chen, Hsuan-Yu, Tsai, Meng-Feng, Lee, Yung-Chie, Yu, Chong-Jen, Shih, Jin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153495/
https://www.ncbi.nlm.nih.gov/pubmed/21858063
http://dx.doi.org/10.1371/journal.pone.0023303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153495/
https://www.ncbi.nlm.nih.gov/pubmed/21858063
http://dx.doi.org/10.1371/journal.pone.0023303

Ejemplares similares