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Including Total EGFR Staining in Scoring Improves EGFR Mutations Detection by Mutation-Specific Antibodies and EGFR TKIs Response Prediction

Epidermal growth factor receptor (EGFR) is a novel target for therapy in subsets of non-small cell lung cancer, especially adenocarcinoma. Tumors with EGFR mutations showed good response to EGFR tyrosine kinase inhibitors (TKIs). We aimed to identify the discriminating capacity of immunohistochemica...

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Detalles Bibliográficos
Autores principales:	Wu, Shang-Gin, Chang, Yih-Leong, Lin, Jou-Wei, Wu, Chen-Tu, Chen, Hsuan-Yu, Tsai, Meng-Feng, Lee, Yung-Chie, Yu, Chong-Jen, Shih, Jin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153495/ https://www.ncbi.nlm.nih.gov/pubmed/21858063 http://dx.doi.org/10.1371/journal.pone.0023303

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