Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
We used a single-trial ERP approach to quantify age-related changes in the time-course of noise sensitivity. A total of 62 healthy adults, aged between 19 and 98, performed a non-speeded discrimination task between two faces. Stimulus information was controlled by parametrically manipulating the pha...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153743/ https://www.ncbi.nlm.nih.gov/pubmed/21833194 http://dx.doi.org/10.3389/fpsyg.2010.00019 |
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author | Rousselet, Guillaume A. Gaspar, Carl M. Pernet, Cyril R. Husk, Jesse S. Bennett, Patrick J. Sekuler, Allison B. |
author_facet | Rousselet, Guillaume A. Gaspar, Carl M. Pernet, Cyril R. Husk, Jesse S. Bennett, Patrick J. Sekuler, Allison B. |
author_sort | Rousselet, Guillaume A. |
collection | PubMed |
description | We used a single-trial ERP approach to quantify age-related changes in the time-course of noise sensitivity. A total of 62 healthy adults, aged between 19 and 98, performed a non-speeded discrimination task between two faces. Stimulus information was controlled by parametrically manipulating the phase spectrum of these faces. Behavioral 75% correct thresholds increased with age. This result may be explained by lower signal-to-noise ratios in older brains. ERP from each subject were entered into a single-trial general linear regression model to identify variations in neural activity statistically associated with changes in image structure. The fit of the model, indexed by R(2), was computed at multiple post-stimulus time points. The time-course of the R(2) function showed significantly delayed noise sensitivity in older observers. This age effect is reliable, as demonstrated by test–retest in 24 subjects, and started about 120 ms after stimulus onset. Our analyses suggest also a qualitative change from a young to an older pattern of brain activity at around 47 ± 4 years old. |
format | Online Article Text |
id | pubmed-3153743 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Frontiers Research Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-31537432011-08-10 Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task Rousselet, Guillaume A. Gaspar, Carl M. Pernet, Cyril R. Husk, Jesse S. Bennett, Patrick J. Sekuler, Allison B. Front Psychol Psychology We used a single-trial ERP approach to quantify age-related changes in the time-course of noise sensitivity. A total of 62 healthy adults, aged between 19 and 98, performed a non-speeded discrimination task between two faces. Stimulus information was controlled by parametrically manipulating the phase spectrum of these faces. Behavioral 75% correct thresholds increased with age. This result may be explained by lower signal-to-noise ratios in older brains. ERP from each subject were entered into a single-trial general linear regression model to identify variations in neural activity statistically associated with changes in image structure. The fit of the model, indexed by R(2), was computed at multiple post-stimulus time points. The time-course of the R(2) function showed significantly delayed noise sensitivity in older observers. This age effect is reliable, as demonstrated by test–retest in 24 subjects, and started about 120 ms after stimulus onset. Our analyses suggest also a qualitative change from a young to an older pattern of brain activity at around 47 ± 4 years old. Frontiers Research Foundation 2010-07-19 /pmc/articles/PMC3153743/ /pubmed/21833194 http://dx.doi.org/10.3389/fpsyg.2010.00019 Text en Copyright © 2010 Rousselet, Gaspar, Pernet, Husk, Bennett and Sekuler. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited. |
spellingShingle | Psychology Rousselet, Guillaume A. Gaspar, Carl M. Pernet, Cyril R. Husk, Jesse S. Bennett, Patrick J. Sekuler, Allison B. Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task |
title | Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task |
title_full | Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task |
title_fullStr | Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task |
title_full_unstemmed | Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task |
title_short | Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task |
title_sort | healthy aging delays scalp eeg sensitivity to noise in a face discrimination task |
topic | Psychology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153743/ https://www.ncbi.nlm.nih.gov/pubmed/21833194 http://dx.doi.org/10.3389/fpsyg.2010.00019 |
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