Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task

We used a single-trial ERP approach to quantify age-related changes in the time-course of noise sensitivity. A total of 62 healthy adults, aged between 19 and 98, performed a non-speeded discrimination task between two faces. Stimulus information was controlled by parametrically manipulating the pha...

Descripción completa

Detalles Bibliográficos
Autores principales: Rousselet, Guillaume A., Gaspar, Carl M., Pernet, Cyril R., Husk, Jesse S., Bennett, Patrick J., Sekuler, Allison B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153743/
https://www.ncbi.nlm.nih.gov/pubmed/21833194
http://dx.doi.org/10.3389/fpsyg.2010.00019
_version_ 1782209933038583808
author Rousselet, Guillaume A.
Gaspar, Carl M.
Pernet, Cyril R.
Husk, Jesse S.
Bennett, Patrick J.
Sekuler, Allison B.
author_facet Rousselet, Guillaume A.
Gaspar, Carl M.
Pernet, Cyril R.
Husk, Jesse S.
Bennett, Patrick J.
Sekuler, Allison B.
author_sort Rousselet, Guillaume A.
collection PubMed
description We used a single-trial ERP approach to quantify age-related changes in the time-course of noise sensitivity. A total of 62 healthy adults, aged between 19 and 98, performed a non-speeded discrimination task between two faces. Stimulus information was controlled by parametrically manipulating the phase spectrum of these faces. Behavioral 75% correct thresholds increased with age. This result may be explained by lower signal-to-noise ratios in older brains. ERP from each subject were entered into a single-trial general linear regression model to identify variations in neural activity statistically associated with changes in image structure. The fit of the model, indexed by R(2), was computed at multiple post-stimulus time points. The time-course of the R(2) function showed significantly delayed noise sensitivity in older observers. This age effect is reliable, as demonstrated by test–retest in 24 subjects, and started about 120 ms after stimulus onset. Our analyses suggest also a qualitative change from a young to an older pattern of brain activity at around 47 ± 4 years old.
format Online
Article
Text
id pubmed-3153743
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Frontiers Research Foundation
record_format MEDLINE/PubMed
spelling pubmed-31537432011-08-10 Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task Rousselet, Guillaume A. Gaspar, Carl M. Pernet, Cyril R. Husk, Jesse S. Bennett, Patrick J. Sekuler, Allison B. Front Psychol Psychology We used a single-trial ERP approach to quantify age-related changes in the time-course of noise sensitivity. A total of 62 healthy adults, aged between 19 and 98, performed a non-speeded discrimination task between two faces. Stimulus information was controlled by parametrically manipulating the phase spectrum of these faces. Behavioral 75% correct thresholds increased with age. This result may be explained by lower signal-to-noise ratios in older brains. ERP from each subject were entered into a single-trial general linear regression model to identify variations in neural activity statistically associated with changes in image structure. The fit of the model, indexed by R(2), was computed at multiple post-stimulus time points. The time-course of the R(2) function showed significantly delayed noise sensitivity in older observers. This age effect is reliable, as demonstrated by test–retest in 24 subjects, and started about 120 ms after stimulus onset. Our analyses suggest also a qualitative change from a young to an older pattern of brain activity at around 47 ± 4 years old. Frontiers Research Foundation 2010-07-19 /pmc/articles/PMC3153743/ /pubmed/21833194 http://dx.doi.org/10.3389/fpsyg.2010.00019 Text en Copyright © 2010 Rousselet, Gaspar, Pernet, Husk, Bennett and Sekuler. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
spellingShingle Psychology
Rousselet, Guillaume A.
Gaspar, Carl M.
Pernet, Cyril R.
Husk, Jesse S.
Bennett, Patrick J.
Sekuler, Allison B.
Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
title Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
title_full Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
title_fullStr Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
title_full_unstemmed Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
title_short Healthy Aging Delays Scalp EEG Sensitivity to Noise in a Face Discrimination Task
title_sort healthy aging delays scalp eeg sensitivity to noise in a face discrimination task
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153743/
https://www.ncbi.nlm.nih.gov/pubmed/21833194
http://dx.doi.org/10.3389/fpsyg.2010.00019
work_keys_str_mv AT rousseletguillaumea healthyagingdelaysscalpeegsensitivitytonoiseinafacediscriminationtask
AT gasparcarlm healthyagingdelaysscalpeegsensitivitytonoiseinafacediscriminationtask
AT pernetcyrilr healthyagingdelaysscalpeegsensitivitytonoiseinafacediscriminationtask
AT huskjesses healthyagingdelaysscalpeegsensitivitytonoiseinafacediscriminationtask
AT bennettpatrickj healthyagingdelaysscalpeegsensitivitytonoiseinafacediscriminationtask
AT sekulerallisonb healthyagingdelaysscalpeegsensitivitytonoiseinafacediscriminationtask