A Twin Study of Mitochondrial DNA Polymorphisms Shows that Heteroplasmy at Multiple Sites Is Associated with mtDNA Variant 16093 but Not with Zygosity

The mitochondrial theory of ageing proposes that damage to mitochondria and diminished mitochondrial DNA (mtDNA) repair are major contributors to cellular dysfunction and age-related diseases. We investigate the prevalence of heteroplasmy in the mtDNA control region in buccal swab and blood derived...

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Detalles Bibliográficos
Autores principales: Andrew, Toby, Calloway, Cassandra D., Stuart, Sarah, Lee, Sang Hoon, Gill, Raj, Clement, Gail, Chowienczyk, Philip, Spector, Tim D., Valdes, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153933/
https://www.ncbi.nlm.nih.gov/pubmed/21857921
http://dx.doi.org/10.1371/journal.pone.0022332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153933/
https://www.ncbi.nlm.nih.gov/pubmed/21857921
http://dx.doi.org/10.1371/journal.pone.0022332

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