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Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model

GBM (glioblastoma multiforme) is a highly aggressive brain tumour with very poor prognosis despite multi-modalities of treatment. Furthermore, recent failure of targeted therapy for these tumours highlights the need of appropriate rodent models for preclinical studies. In this review, we highlight t...

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Detalles Bibliográficos
Autores principales: Jacobs, Valerie L, Valdes, Pablo A, Hickey, William F, De Leo, Joyce A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153964/
https://www.ncbi.nlm.nih.gov/pubmed/21740400
http://dx.doi.org/10.1042/AN20110014