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A Key Role for Membrane Transporter NKCC1 in Mediating Chondrocyte Volume Increase in the Mammalian Growth Plate

The mechanisms that underlie growth plate chondrocyte volume increase and hence bone lengthening are poorly understood. Many cell types activate the Na-K-Cl cotransporter (NKCC) to bring about volume increase. We hypothesised that NKCC may be responsible for the volume expansion of hypertrophic chon...

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Detalles Bibliográficos
Autores principales: Bush, Peter G, Pritchard, Meredith, Loqman, Mohamad Y, Damron, Timothy A, Hall, Andrew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154001/
https://www.ncbi.nlm.nih.gov/pubmed/20200963
http://dx.doi.org/10.1002/jbmr.47