Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes

Elucidation of natural product biosynthetic pathways provides important insights about the assembly of potent bioactive molecules, and expands access to unique enzymes able to selectively modify complex substrates. Here we show full reconstitution in vitro of an unusual multi-step oxidative cascade...

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Detalles Bibliográficos
Autores principales: Carlson, Jacob C., Li, Shengying, Gunatilleke, Shamila S., Anzai, Yojiro, Burr, Douglas A., Podust, Larissa M., Sherman, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154026/
https://www.ncbi.nlm.nih.gov/pubmed/21778983
http://dx.doi.org/10.1038/nchem.1087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154026/
https://www.ncbi.nlm.nih.gov/pubmed/21778983
http://dx.doi.org/10.1038/nchem.1087

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