LKB1/PEA3/ΔNp63 Pathway Regulates PTGS-2 (COX-2) Transcription in Lung Cancer Cells Upon Cigarette Smoke Exposure

This is the first study to show that cigarette smoking induced the LKB1/PEA 3/ΔNp63-dependent transcriptional regulation of inflammatory molecules, such as COX-2/PTGS-2. Using mainstream smoke extract (MSE) and sidestream smoke extract (SSE) as modeling tools for primary and secondhand smoking, we f...

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Detalles Bibliográficos
Autor principal: Ratovitski, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154041/
https://www.ncbi.nlm.nih.gov/pubmed/21150337
http://dx.doi.org/10.4161/oxim.3.5.13108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154041/
https://www.ncbi.nlm.nih.gov/pubmed/21150337
http://dx.doi.org/10.4161/oxim.3.5.13108

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