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Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences

BACKGROUND: Renal kallikrein (KLK1) synthesis and urinary excretion are reportedly diminished during AKI (acute kidney injury) in animal models, and provision of kallikrein abrogates renal injury in this setting, but data in human AKI is limited. Therefore we first examined KLK1 renal excretion in h...

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Detalles Bibliográficos
Autores principales: Kang, Sun Woo, Shih, Pei-an Betty, Mathew, Roy O, Mahata, Manjula, Biswas, Nilima, Rao, Fangwen, Yan, Liying, Bouchard, Josee, Malhotra, Rakesh, Tolwani, Ashita, Khandrika, Srikrishna, Mehta, Ravindra L, O'Connor, Daniel T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154145/
https://www.ncbi.nlm.nih.gov/pubmed/21679467
http://dx.doi.org/10.1186/1471-2369-12-27