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Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity

BACKGROUND: Methionine aminopeptidase (MetAP) is a ubiquitous enzyme in both prokaryotes and eukaryotes, which catalyzes co-translational removal of N-terminal methionine from elongating polypeptide chains during protein synthesis. It specifically removes the terminal methionine in all organisms, if...

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Detalles Bibliográficos
Autores principales: Kanudia, Pavitra, Mittal, Monica, Kumaran, Sangaralingam, Chakraborti, Pradip K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154147/
https://www.ncbi.nlm.nih.gov/pubmed/21729287
http://dx.doi.org/10.1186/1471-2091-12-35