Cargando…

Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity

BACKGROUND: Methionine aminopeptidase (MetAP) is a ubiquitous enzyme in both prokaryotes and eukaryotes, which catalyzes co-translational removal of N-terminal methionine from elongating polypeptide chains during protein synthesis. It specifically removes the terminal methionine in all organisms, if...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kanudia, Pavitra, Mittal, Monica, Kumaran, Sangaralingam, Chakraborti, Pradip K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154147/ https://www.ncbi.nlm.nih.gov/pubmed/21729287 http://dx.doi.org/10.1186/1471-2091-12-35

Ejemplares similares

MapB Protein is the Essential Methionine Aminopeptidase in Mycobacterium tuberculosis
por: Vanunu, Miriam, et al.
Publicado: (2019)

Amino Acids Involved in Polyphosphate Synthesis and Its Mobilization Are Distinct in Polyphosphate Kinase-1 from Mycobacterium tuberculosis
por: Mittal, Payal, et al.
Publicado: (2011)

Methionine: An Indispensable Amino Acid in Cellular Metabolism and Health of Atlantic Salmon
por: Espe, M., et al.
Publicado: (2023)

The Role of Methionine Aminopeptidase 2 in Lymphangiogenesis
por: Esa, Rawnaq, et al.
Publicado: (2020)

Cholesterol Oxidase Is Indispensable in the Pathogenesis of Mycobacterium tuberculosis
por: Klink, Magdalena, et al.
Publicado: (2013)

Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis
por: Venos, Erik S, et al.
Publicado: (2004)

Analysis of the stoichiometric metal activation of methionine aminopeptidase
por: Chai, Sergio C, et al.
Publicado: (2009)

Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity
por: Joharapurkar, Amit A, et al.
Publicado: (2014)

Methionine aminopeptidase-2 is a pivotal regulator of vasculogenic mimicry
por: Shimizu, Shota, et al.
Publicado: (2022)

The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis
por: You, CongHui, et al.
Publicado: (2005)

A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus
por: Labrie, Simon J., et al.
Publicado: (2019)

The Activity of a Hexameric M17 Metallo-Aminopeptidase Is Associated With Survival of Mycobacterium tuberculosis
por: Correa, Andre F., et al.
Publicado: (2017)

Characterisation of methionine adenosyltransferase from Mycobacterium smegmatis and M. tuberculosis
por: Berger, Bradley J, et al.
Publicado: (2003)

Brain Signaling of Indispensable Amino Acid Deficiency
por: Gietzen, Dorothy W.
Publicado: (2021)

Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani
por: Kumar, Ritesh, et al.
Publicado: (2017)

Author Correction: A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus
por: Labrie, Simon J., et al.
Publicado: (2020)

Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition
por: Bainbridge, John, et al.
Publicado: (2007)

Early Treatment with Fumagillin, an Inhibitor of Methionine Aminopeptidase-2, Prevents Pulmonary Hypertension in Monocrotaline-Injured Rats
por: Kass, Daniel J., et al.
Publicado: (2012)

Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes
por: Ma, Ze-Qiang, et al.
Publicado: (2007)

NC2213: a novel methionine aminopeptidase 2 inhibitor in human colon cancer HT29 cells
por: Selvakumar, Ponniah, et al.
Publicado: (2009)

Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase
por: Baas, Bert-Jan, et al.
Publicado: (2014)

Aminopeptidases
por: Sanz, Yolanda
Publicado: (2007)

Extensively Drug-Resistant Mycobacterium tuberculosis, India
por: Mondal, Rajesh, et al.
Publicado: (2007)

Involvement of arginine 878 together with Ca(2+) in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues
por: Couvineau, Pierre, et al.
Publicado: (2017)

Phosphonic Acid Analogues of Phenylglycine as Inhibitors of Aminopeptidases: Comparison of Porcine Aminopeptidase N, Bovine Leucine Aminopeptidase, Tomato Acidic Leucine Aminopeptidase and Aminopeptidase from Barley Seeds
por: Wanat, Weronika, et al.
Publicado: (2019)

In silico identification of microRNAs predicted to regulate N-myristoyltransferase and Methionine Aminopeptidase 2 functions in cancer and infectious diseases
por: Chauhan, Ranjit, et al.
Publicado: (2018)

Identification of promising methionine aminopeptidase enzyme inhibitors: A combine study of comprehensive virtual screening and dynamics simulation study
por: Alabbas, Alhumaidi B.
Publicado: (2023)

Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 2
por: Watanabe, Natsuki, et al.
Publicado: (2023)

Secreted Acid Phosphatase (SapM) of Mycobacterium tuberculosis Is Indispensable for Arresting Phagosomal Maturation and Growth of the Pathogen in Guinea Pig Tissues
por: Puri, Rupangi Verma, et al.
Publicado: (2013)

Longitudinally extensive transverse myelitis with mycobacterium tuberculosis infection
por: Fang, Le, et al.
Publicado: (2021)

Aminopeptidase N
por: Turner, Anthony J.
Publicado: (2013)

Discovery of a New Genetic Variant of Methionine Aminopeptidase from Streptococci with Possible Post-Translational Modifications: Biochemical and Structural Characterization
por: Arya, Tarun, et al.
Publicado: (2013)

Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction
por: Ochiya, Takahiro, et al.
Publicado: (2015)

The Potential Role of the Methionine Aminopeptidase Gene PxMetAP1 in a Cosmopolitan Pest for Bacillus thuringiensis Toxin Tolerance
por: Ye, Min, et al.
Publicado: (2022)

A First-in-human, Dose-escalation Study of the Methionine Aminopeptidase 2 Inhibitor M8891 in Patients with Advanced Solid Tumors
por: Carducci, Michael A., et al.
Publicado: (2023)

Nucleoside diphosphate kinase from Mycobacterium tuberculosis cleaves single strand DNA within the human c-myc promoter in an enzyme-catalyzed reaction
por: Kumar, Praveen, et al.
Publicado: (2005)

Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis
por: Howe, Michael D., et al.
Publicado: (2018)

The amino‐terminal domain of Mycobacterium tuberculosis ClpB protein plays a crucial role in its substrate disaggregation activity
por: Tripathi, Prajna, et al.
Publicado: (2018)

Can the digestible indispensable amino acid score methodology decrease protein malnutrition
por: Bailey, Hannah M, et al.
Publicado: (2019)

Digestible Indispensable Amino Acid Scores (DIAAS) of Six Cooked Chinese Pulses
por: Han, Fei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ju5ijmehfi0mdtfm6sgb7j224m