Cargando…

E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion

BACKGROUND: E7080 is an orally active multi-targeted kinase inhibitor whose targets include vascular endothelial growth factor receptors (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptors (PDGFR). It has been shown to inhibit tumor angiogenesis by targetin...

Descripción completa

Detalles Bibliográficos
Autores principales: Glen, Hilary, Mason, Susan, Patel, Hitesh, Macleod, Kenneth, Brunton, Valerie G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154179/
https://www.ncbi.nlm.nih.gov/pubmed/21781317
http://dx.doi.org/10.1186/1471-2407-11-309