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Hierarchical Differentiation of Myeloid Progenitors Is Encoded in the Transcription Factor Network
Hematopoiesis is an ideal model system for stem cell biology with advanced experimental access. A systems view on the interactions of core transcription factors is important for understanding differentiation mechanisms and dynamics. In this manuscript, we construct a Boolean network to model myeloid...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154193/ https://www.ncbi.nlm.nih.gov/pubmed/21853041 http://dx.doi.org/10.1371/journal.pone.0022649 |