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Hierarchical Differentiation of Myeloid Progenitors Is Encoded in the Transcription Factor Network

Hematopoiesis is an ideal model system for stem cell biology with advanced experimental access. A systems view on the interactions of core transcription factors is important for understanding differentiation mechanisms and dynamics. In this manuscript, we construct a Boolean network to model myeloid...

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Detalles Bibliográficos
Autores principales: Krumsiek, Jan, Marr, Carsten, Schroeder, Timm, Theis, Fabian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154193/
https://www.ncbi.nlm.nih.gov/pubmed/21853041
http://dx.doi.org/10.1371/journal.pone.0022649