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A Bayesian Method for Evaluating and Discovering Disease Loci Associations

BACKGROUND: A genome-wide association study (GWAS) typically involves examining representative SNPs in individuals from some population. A GWAS data set can concern a million SNPs and may soon concern billions. Researchers investigate the association of each SNP individually with a disease, and it i...

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Detalles Bibliográficos
Autores principales: Jiang, Xia, Barmada, M. Michael, Cooper, Gregory F., Becich, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154195/
https://www.ncbi.nlm.nih.gov/pubmed/21853025
http://dx.doi.org/10.1371/journal.pone.0022075