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Aristolochic acid I and ochratoxin A differentially regulate VEGF expression in porcine kidney epithelial cells—The involvement of SP-1 and HIFs transcription factors

Aristolochic acid I (AAI) and ochratoxin A (OTA) cause chronic kidney diseases. Recently, the contribution of hypoxic injuries and angiogenic disturbances to nephropathies has been suggested, but underlying mechanisms have not been fully clarified yet. In porcine kidney epithelial cell line, LLC-PK1...

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Detalles Bibliográficos
Autores principales: Stachurska, Anna, Kozakowska, Magdalena, Jozkowicz, Alicja, Dulak, Jozef, Loboda, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154282/
https://www.ncbi.nlm.nih.gov/pubmed/21554934
http://dx.doi.org/10.1016/j.toxlet.2011.04.022