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Snail Involves in the Transforming Growth Factor β1-Mediated Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells

BACKGROUND: The proliferation of retinal pigment epithelium (RPE) cells resulting from an epithelial-mesenchymal transition (EMT) plays a key role in proliferative vitreoretinopathy (PVR), which leads to complex retinal detachment and the loss of vision. Genes of Snail family encode the zinc finger...

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Detalles Bibliográficos
Autores principales: Li, Hui, Wang, Hongwei, Wang, Fang, Gu, Qing, Xu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154444/
https://www.ncbi.nlm.nih.gov/pubmed/21853110
http://dx.doi.org/10.1371/journal.pone.0023322